N-Boc-cis-4-hydroxy-D-proline (135042-12-5) - APICMO Ko APICMO he kaiwhakarato o te hanganga ritenga ahumahi me te kirimana R & D Kāinga Mō Us To tatou Tikanga to tatou kiritaki To tatou Team to tatou Ratonga Rangahau me te kirimana R & D Te ahumahi iti me te ahumahi nui Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Tukuangé press Products Whakapā mai Kāinga Mō Us To tatou Tikanga to tatou kiritaki To tatou Team to tatou Ratonga Rangahau me te kirimana R & D Te ahumahi iti me te ahumahi nui Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Tukuangé press Products Whakapā mai Hua Products > N-Boc-cis-4-hydroxy-D-proline (135042-12-5) N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakatauria 5.00 i roto o 5 i runga i 1 whakatauranga kiritaki ( 2 arotake kiritaki) Kei te noho tenei hua (s) i runga i te kirimana APICMO. Ko te kaha ki te whakaputa, te whakahiato me te waihanga i te rahi o te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) me te pūnaha whakahaere kounga i raro i te hangahanga CGMP ture. Kāwai: Ngā pūhui chiral Whakaahuatanga Reviews (2) Whakaahuatanga Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) ataata Kei te APICMO te tini o nga hua e uru ana ki te N-Boc-cis-4-hydroxy-D-proline (135042-12-5). Ko te waahanga o nga kaitautoko. Whakapā mai mo etahi atu korero. Kei te noho tenei hua (s) i runga i te kirimana APICMO. Mena kei te tiro koe i tenei whārangi hei kaiwhakamahi kore-rēhitatia, ko te utu (s) e whakaatuhia ana ko te Utu Rārangi. Hei tiro i to utu, takiuru ma te whakamahi i to tau nama, ka riro hei kaiwhakamahi rēhitatia mā te whakapā atu ki tetahi o o tatou ratonga Ratonga Kiritaki. Ki te whakatakoto i tetahi tono, whakapā atu ki te Ratonga Kiritaki a APICMO. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakaahuatanga CAS 135042-12-5 CAS Min% 95% CAS Max% 100% Tau MDL MFCD02094407 Ki te KAUPAPA KI BENKAPCDIOILGV-RNFRBKRXSA-N Ingoa Toiina, Rauemi ranei N-Boc-cis-4-hydroxy-D-proline Hauira Purapura Motuhēhē Puka Puka Packaging Pounamu tio Tātai rāpoi C10H17NO5 Taumaha Taumaha (g / mol) 231.25 Tuhinga o mua CC (C) (C) OC (= O) N1C [ [Tiakina email] ] (O) C [ [Tiakina email] @H] 1C (= O) O Tae Ko te Whakakuku 146-151 ° C anga matou 97% N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Te Haumaru me te Whakaaetanga (135042-12-5) GHS H Statement H319 Ka nui te riri o te kanohi. Ko te N-Boc-cis-4-hydroxy-D-proline GHS P Statement P264+P280+P305+P351+P338+P337+P313 Horoi i te kiri i muri i te mahinga Whakanohoia nga maru haumaru / tiaki kanohi / kanohi MĀ TE KAUPAPA: Whakakotahitia te wai ki te wai mo etahi meneti. Tangohia te arotahi atu ki nga arotahi, ki te mea ka kitea, me te ngawari ki te mahi. Haere tonu ki te horoi. Mena kei te mau tonu te riri o te kanohi: Haere ki te tohutohu hauora / aro. WHAKATŪPATO: Ko nga korero i whakawhiwhia ki tenei pae tukutuku i whakawhanaketia i raro i nga ritenga o te ture a te Euroopu (EU) me te tika ki to maatau mohio, korero me te whakapono i te ra i tuhia ai. Ko nga korero i homai i hangaia hei awhina mo te whakahaere me te whakamahi haumaru. Kaore e whakaarohia he waahana, he kounga kounga. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Nga tuhinga He huarahi hou pai mo te whakarite o (4R) -1- (tert-butoxycarbonyl) - 4-amino-D-proline Kua whakaatuhia e mätou he huarahi hou hei whakapai ake i te (4R) -1- (tert-butoxy-carbonyl) -4-amino-D-proline mai i te cis-4-hydroxy-D-proline ma te whakamahi i nga matū kore iti e iti ana te utu. rite te konutai azide me te triphenylphospine mo te wa tuatahi i roto noa i te wha nga kaupae Pukapuka Indian o Heterocyclic Chemistry 2003 vol. 12 # 4 p. 381 - 382 He tikanga hangarau hou mo te whakarite i nga huakawa a-a, β-didehydroamino waikawa na roto i te ahua o te whakautu. Nga tihana o (2S, 4S) - a (2R, 4R) -4-hydroxyprolines Ko te Ethyl N-Boc- me te NZ-α-tosylglycinates i whakatutukihia me etahi momo aldehydes i te aroaro o te tributylphosphine me te turanga ki te tuku i nga huakawa a-α, β-didehydroamino me te teitei (Z) -selectivity i nga hua pai. I tua atu, ka hurihia te taiao (4S) - me te (4R) -2- (N-Boc-amino) -4,5-isopropylidenedioxy-2-pentenoates i hangaia e te tikanga o teianei (2S, 4S) - a (2R, 4R) - 4-hydroxyprolines, ia. Tuhinga o mua o te Japan Society 2002 vol. 75 # 11 p. 2517 - 2525 Ratonga Hangarau: Kei to tatou kapa o nga kaitaiao nga wheako ki nga waahanga katoa o te rangahau, tae atu ki te Life Science, Te Hangarau Rauemi, te Hinengaro Hinairo, te Chromatography, te Tatauranga me etahi atu. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakahua Puku & Tauira: Me nui ake nga waahanga mo to whakawhanaketanga, mahi mahi, rangahau ranei? ingoa hua ingoa * īmēra * waea Whakaahua * CAPTCHA * = tākupu tuku 2 arotake hoki N-Boc-cis-4-hydroxy-D-proline (135042-12-5) APICMO - 12 / 11 / 2018 He maha nga wa kaore pea koe e tino mohio ki hea e hoko ai i to hua hua koiora pai. Kaore e pai ake, i te APICMO ka whakarato koe ki a koe i te wheako hokohoko pai kua oti ia koe. Ka whakaratohia e matou ki a koe nga hua matomato ki te tino whakataetae. Ko matou te kamupene rongoa rongoa e hanga ana i te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) i roto i etahi atu hua matū. Ko o taatau hua katoa kei te pai ki te Whakangungu Mahi Pai Katoa me etahi atu whakaritenga ahumahi. Tukuna mai i a matou i tenei ra ka tuku atu ki a koe te pai o te ao. Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Te Hanga Taiao Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Rohe Hinonga N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Waitohu o Mua me te Ahumahi o raro kawainga Hua Rawa N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Nga Koreroto 135042-12-5 N-Boc-cis-4-Hydroxy-D-proline Boc-cis-4-Hydroxy-D-proline (2R, 4R) -1- (tert-butoxycarbonyl) -4-hydroxy (2R, 4R) -N-Boc-4-hydroxypyrrolidine-2-carb UNII-I467853HPL I467853HPL N-Boc-4-hydroxy-D-proline, cis- (4R) -1- (tert-butoxycarbonyl) -4-hydroxy-Dp (2R, 4R) -N-Boc-4-hydroxy-2-pyrrolidinecarb N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakaahuatanga Hua viivii 98% State State paura Monoisotopic Mass (g / mol) 231.111 Taumaha Taumaha (g / mol) 231.248 Tātai rāpoi C10H17NO5 Ko te Whakakuku 146-151 ˚c Ingoa IUPAC (2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid kiato 1.312 g / cm ^ 3 Ingoa Toi N-Boc-cis-4-Hydroxy-D-proline Te wai kohua 390.9 ˚c i 760 mmHg Papanga Flash 190.2 ˚c Kore CAS 135042-12-5 N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Ngā Āhuatanga Tinana me te Taiao ahua He mea ma-te ma ki te paura ma. hononga Ko te Tae 1 Puri Rotatable 3 Te waihanga wai Acceptor-5 Donor-2 pūmautanga Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) e tu ana i nga tikanga noa. Ka pahemo i te wa e pa ana ki te wera nui ki te whakaputa i nga waikawa hauota, te konupora o te karo, me te monowaro karo. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Ngā āhuatanga kua whakaritea. TE WHAKAMAHI MANA Tuhinga o mua Atomope Atom Te tatau 0 Te Tae Tae Tae Taehia Kore 0 Tae Tae Tae Tautuhia 0 Te Tautuhi Tae Akerangi Atomorekore 0 Tautuhia te Tohu Toro o Atom 2 Maatau Atom Count 16 Tae Whaimana 0 Ka taea te Whakauruhia te Hanga pono XLogP3-AA 0.3 Motuhake Mae 231.111 g / mol Te Porow Area Polar Area 87.1 A ^ 2 CACTVS Te Hanga Tohu Paerewa Matua AAADCEBYOAAAAAAAAAAAAAAAAAAAAW AAAAAAAAAAAAAAAAAAAAAAHGAACAAA DHzhgAYCCAMABgAIAACQGAAAAAAAAAA AAAGIAAACEBIAGCAMQAAGBGCQAADAEQIA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA == Tuhinga 296 He raruraru e pa ana ki te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Ka whakapataritari te kiri i te kiri i te wa e pa ana ki a ia. Ka taea e te kiri o te kiri, te pupuhi, me te wera. Ka whakapataritarihia e ia te rorohiko o te waahanga rewharewha o runga i te wa kotahi. Ka arai i te pupuhi o te ihu, te hukahuka, te whakawhiti ira, te korokoro, me te mare. He kino te mata ki nga kanohi i te wa e pakaru ana i roto ia ratou. Ka arahina te kanohi ki te whakaata, ki te whakainu, ki te mamae, me te kite matakite. He mea paowa tetahi i whakauruhia. Ka meinga pea e te mate te mate, te mamae o te kopu / te ahuakore me te kore o te hiahia. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Nga Tikanga Haumaru 1. Te tiaki whaiaro Te tiaki hauora Me mahi he aromatawai hei whakatau mehemea he hiahia ki te whakamahi i nga hauora mo te whakakii i te hau mo te mahi e mahi ana koe. Mena ka taunakitia e ia tana whakamahinga, ka mau i te kaehu o te ahua N95 (US), i te momo P1 (EN 143) ranei. Mo te whakamahinga teitei te whakamahi i te momo ABEK-P2 (EU EN143) ka pato i te OV / AG / P99 (US). Whakamahia i nga wa katoa te whakamatau me te whakaaha i nga hikoihana i raro i nga paerewa a te kawanatanga e tika ana mo te CEN (EU) me te NIOSH (US). Te tiaki kiri me te tinana Me whiriwhiri koe i te kiri tika me te taputapu tiaki tinana e ai ki te nui me te kukume o te taonga kino i to mahi. Mo te haumaru teitei, whakamahia nga huu me nga kakahu e kore e pai. I te iti rawa, me noho koe i roto i nga huinga-tatae me te koti. Tiaki kanohi Hei pare i nga kowhatu o te kanohi, ka mau i nga karaihe haumaru ki nga whakangungu rakau e rite ana ki te EN I66. Kia mohio koe he pai te whakamatautau mo te tiki karaihe o to rahi ki te whakarite kia whai hua. Whakamahia nga kakahu tiaki kanohi me te whakaaetia i roto i nga paerewa a te kawanatanga e tika ana kia rite ki te EN 166 (EU) me te NIOSH (US). Tiaki ringa Whakanohoia nga maru haumaru e makona ana i nga whakaritenga o te rautaki a te EU 89 / 686 / EEC me te paerewa EN 374 i puta mai. Me mohio kaore nga roimata e uimata i mua i te kakahu. I muri i te whakamahinga, tangohia ma te whakamahi i te taputapu tango moenga me te kore e uru atu ki te mata o waho. Peia atu kia hohoro te horoi i a ratau mehemea ka taea te whakamahi. 2. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakahaere Engineering Whakanohia nga taputapu horoi kanohi / tinana i roto i te takiwa o te rohe mahi. Ka whakarite i te urupare tere i te wa o te raruraru. Ka taea e nga taputapu te whakakore atu i nga kirihi i runga i te tinana me nga kanohi, ka maka atu i te ahi ki runga i nga kakahu ka puta mai he ahi, he urupare tinana ranei. Me whakarite he mahinga tika i roto i te takiwa e mahi ana koe i ngaa waahi kei nga waahi iti o te waahanga o te hau, kei hea hoki te hanganga o te puehu. Ko te whakamahi i nga hopi me te whakaurutanga o nga hanganga hauora o te rohe e mahi. Whakaaetia nga ture katoa o te motu / rohe. 3. Nga mema awhina tuatahi I muri i te whakamahuratanga Tangohia te kaipupuri mai i te waahi ka kitea, ka kawe ia ki te hau hou. Me noho ratou ki te turanga kia taea ai e ratou te hangai hihiri. Mena kaore i te pupuhi, hoatu ki a raatau te taangata, mehemea ka taea e te mangai ki te mangai. Mena he uaua ki te hau, whakahaerehia te konupora. Tirohia tetahi taakuta. I muri i te whakapiri kiri Whakapaia te rauemi i waho o te kiri me te nui o te wai rere me te hopi kore-abrasive mo te iti rawa o nga meneti 15, ina tangohia atu e koe etahi kakahu pokekore ranei huinga. Ka taea e koe te whakamahi i te wai matao. Ka hipoki i te wahi e pa ana ki te kaimuri. Mena ka pupuhi, ka whero, ka pupuhi nga rama, ka rapu wawe koe i te taote. I muri i te kanohi kanohi Whakapakia nga kanohi ki te nui o te wai. Mena kei te whai koe i nga arotahi whakapiri, kaore i puta atu i te wa o te whakaheke, tangohia. Whakanohia i raro i nga kamo ma te wehewehe ia ratou ma te whakamahi i ou maihao. Me whakarite kia tuwhera nga kanohi. Ka taea e koe te whakamahi i te wai koiora. Mena te pupuhi, te whero, te whanaketanga o te wera, me rapu te taote kia tirotiro me te hamani i ou kanohi. I muri i te waihanga Mena ka mohio te kaipupuri, me whakamahi i te wai hei horoi i to ratau waha mo nga meneti 15 rawa. Kaua e hoatu tetahi mea kaore i kitea i roto i te mangai. Kaua e tukuna i te ruaki kaore he tohutohu a te rata, he pokapū kawa ranei. 4. I te whakamahi i te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakaaetia nga ture haumaru katoa mo te whakamahinga o nga hua matū. Whakamahia tenei hua i roto i te hopi whakakino. Kaua e pupuhi i te puehu, i nga waatea ranei e hua mai nei, no te mea he mea kino ki a ratou. Me whakarite he mahinga tika i roto i te waahi mahi. Whakamahia anake i roto i te huikoi matomato. Me mohio kei a koe he taputapu haumaru kore. Kaua e kai, inu, paowa ranei ka whakamahi i tenei hua ka taea e te waihanga. Me mohio kei te tata ki a koe nga teihana kanohi, nga waatea haumaru, me nga taputapu pakaru. Me whakarite e whakamahi ana i nga waahanga pai mo te tautuhi ake i te tautuhi. 5. I muri i te whakamahi i te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Whakahokia te hua matū i roto i tana rohe rokiroki. Tangohia te taputapu tiaki me te horoi i te reira, ka tuku kia hurihurihia i mua i te peke. Whakaritea nga mea katoa me nga otaota ka tika. Whakapaia te mahinga mahi kia kore ai he putea e mahue. Whakapaia nga ringa kia tino whakamarokehia e koe ma te whakamahi i te taera horoi kia kore ai e whakahou. 6. A, no te whakamahi i Me hiritia te ipu ki te hua toenga. Me whakarite he pai te tohu. Tiakina tenei hua mai i nga kaimahi kore, kaore i te waitohu, kaore hoki i te tika. I te wa e mahi ana koe ki a koe, kaua e waiho nga ipu ki runga ki runga ki runga ki runga ki te karo i nga pakaru. Tuhia ki te wahi raumati he nui te hanganga o te hau, a, ko te mea kaore i nga puna ahi me nga mea matatini kore. 7. Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) me te rokiroki whāwhā Mawehe i te kiri me te kanohi ki tenei hua matū, he mea kino. A ape i te whakawhitinga roa. Whakamahia te nui o te tupato me te whakahaere i tenei hua. A ape i te whakauru i te pupuhi, te kohu, me nga paraoa i whakaputaina e tenei hua. Kaua e paowa, me te pupuri i te hua mai i nga puna o te riri mai i te mea he mura ana. Whakamahia nga rautaki hei awhina i te hanganga o te kawenga electrostatic. Kaua e tukua te hua ki te uru ki roto. Storage Tiakihia nga hua mai i nga matatini kaore i te whaitake ki te aukati i tetahi hohenga mai i te waahi. Whakaorangia i te mea ka piri tonu ki te karo i nga pakaru. Kaua e kai, kaua hoki e rongoa i te kai, te inu, te paaka ranei i nga waahi kua tupu pea te hua o tenei hua matū. 8. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Nga waahanga mate Te waipuke Kei roto i te putea ma te whakamahi i te parenga tika kia kore ai e rere haere. Whakanohia he hikoiho tika, he taputapu roera taimaha, me nga huinga. Whakaranuhia te toenga ki te onepu ranei te ahua o nga mea mimiti raima, te kapi / tepe / te panaa me te whakawhiti ki roto i tetahi oko e tika ana kia whakakorea. Ina oti, horoia te rohe ka whakahurihurihia. Horoihia te kiri tonu me te nui o te wai ma, ka maroke. Kaua tenei hua matū e tae ki nga awaawa, ki nga waaawa. Mena he nui rawa te putea mo koe ki te whakahaere, whakawhiti atu ki te kamupene riihi mo te awhina. Mana ahi Tangohia nga tāngata katoa i roto i te whakaaturanga. Whakanuia nga ipu kawe katoa ki tetahi wahi haumaru mēnā ka taea, ka haumaru hoki ki te mahi. Whakanohia he taputapu hihoki me te kakahu tiaki mo te kore e pa ki te kiri me nga kanohi. Whakamahia tetahi o nga korero whakamapuku e whai ake nei: Te waipiro waipiro Te paura matū Koropiro konupora 9. Te aronga me te tauhohenga Ko te N-Boc-cis-4-hydroxy-D-proline (135042-12-5) e whakahoa ana ki nga kaitohu waikura kaha, nga waikawa kaha me nga turanga. 10. Te tangohanga matū Ka taea e koe te tahu i roto i te whakauru kua oti te whakakakahu me te kapi me te kaimutu. Kia tupato ano koe i te wa e whakakorea ana e te mea he tino mura te mea nei. Ka taea hoki e koe te tuku utu me te kore e taea te whakamahi i nga rongoā ki te kamupene riihi e tuku ana i te raihana. Ko tetahi atu huarahi ko te whakapā atu ki tetahi kamupene urupare raihana raihana hei awhina ia koe ki te tango i te otaota matū. 11. ōta mōhiohio N-Boc-cis-4-hydroxy-D-proline (135042-12-5) e haumaru ana ki te kawe i te hau, te wai, me te huarahi. N-Boc-cis-4-hydroxy-D-proline (135042-12-5) Te utu nui me te tono Ahakoa e hiahiatia ana e koe i roto i te iti, i te nui ranei o te rahi, i hipokina koe e koe. Whakapā mai ki a matou i tenei ra mo nga uiuinga ka taea e koe. Bibliography Chem Sources USA, Whakahaere Kamupene Whakaputa, Incorporated, 2004, te Whare Wānanga o Michigan, whārangi 200. Te ahunga whakamua i te Tikanga Hauora, Volume 34, page 23.3 Te Taiwhanga Hinengaro o Chiral Compounds: Te Tauanga me nga Whakamahinga, Christian Wolf, Georgetown University, Washington DC, page 204-304. National Center For Information Biotechnology, US. National Library of Medicine, PubChem, N-Boc-cis-4-hydroxy-D-proline, Wāhanga 1-8. Whakatauria 5 i roto i o 5 Apicmo - 05 / 17 / 2019 Ko te N-Boc-cis-4-hydroxy-D-proline tino pai me te ratonga kua riro i ahau, he wheako pai Tāpiri i te arotake Whakakore whakautu Ka kore e whakaputaina tō wāhitau īmēra. tō whakatauranga Auau ... tino Pai Toharite E kore e kino Tino rawakore tō arotake * ingoa * īmēra * e pā ana Products Boc-CIS-4-HYDROXY-L-PROLINE (87691-27-8) na APICMO Pānuitia atu Cis-4-Hydroxy-D-proline (2584-71-6) na APICMO Pānuitia atu (S)-(-)-2-Methyl-2-propanesulfinamide (343338-28-3) na APICMO Pānuitia atu Rapu hoki: Rapu Ngā Kāwai Hua Pūhui Spiro Azetidines Heterocycles Nga potae Nga pounamu Qungazolines Nga pungarehu Ngā pūhui chiral Ētahi atu pūhui Orthe Tūtohu hua Tuhinga Kāwai Tuhinga Kāwai Tīpako Kāwai Ko te tuhinga CMO (2) Ko te matauranga hauora (7) Nga Releata Hou 2019 CNS Treatment Drug Monosialotetrahexosylganglioside Sodium (GM1) Pig Brain (37758-47-7) 06 / 05 / 2019 Ko nga mea katoa e hiahia ana koe ki te mohio ki nga Pyridines 08 / 30 / 2018 Ko te nuinga o nga Taonga Hiko o te Ao 08 / 28 / 2018 Ko nga mea katoa e hiahia ana koe ki te mohio ki nga waehui spiro 08 / 28 / 2018 2-Chloro-5-methylpyrimidine: CAS (Ratonga Tapeke Tika) Waitohu 22536-61-4 08 / 18 / 2018 APICMO - Pakihi, APICMO & Pharmaceutical te hoko NOW Ko APICMO he kamupene rongoa kei te whanake i nga kaiwawao matua o nga raau hou. Kei te arotahi ki te whakarato i te raupapa katoa o nga ratonga whakahiato me te whakarite mo nga rangahau raau taero me nga pokapü whanaketanga me nga kamupene rongoa. Products Ētahi atu pūhui Nga pounamu Heterocycles Qungazolines Nga potae Ngā pūhui chiral Azetidines Nga pungarehu Pūhui Spiro to tatou Ratonga Ko te whakawhitinga ahurea me te kirimana R & D Pauna iti me te raupapa whakahau Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Whakapā mai Te hanga D, te papa 2, Nama 128, Road Xiangyin, Takiwa o Yangpu, 200433, Shanghai, Haina + 86 (1812) 4514004 [Tiakina email] © Copyright 2019 APICMO. 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