147804-30-6 - APICMO R & D Center - Pūhui Spiro Ko APICMO he kaiwhakarato o te hanganga ritenga ahumahi me te kirimana R & D Kāinga Mō Us To tatou Tikanga to tatou kiritaki To tatou Team to tatou Ratonga Rangahau me te kirimana R & D Te ahumahi iti me te ahumahi nui Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Tukuangé press Products Whakapā mai Kāinga Mō Us To tatou Tikanga to tatou kiritaki To tatou Team to tatou Ratonga Rangahau me te kirimana R & D Te ahumahi iti me te ahumahi nui Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Tukuangé press Products Whakapā mai Hua Products > Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Whakatauria 5.00 i roto o 5 i runga i 1 whakatauranga kiritaki ( 2 arotake kiritaki) Kei te noho tenei hua (s) i runga i te kirimana APICMO. Ko te kaha ki te whakaputa, ki te whakarahi me te waihanga i te rahi o te tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) me te pūnaha whakahaere kounga i raro i te hangahanga CGMP ture. Kāwai: Pūhui Spiro Whakaahuatanga Reviews (2) Whakaahuatanga tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) video Ko te Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate he pūhui spiro. Kei te whai a Spiro he kinukore kinasere kinoa, tae atu ki te c - Ka mahi i nga mahi a te hinengaro o te tyrosine kinase me nga mea penei, ka taea te whakamahi mo te maimoatanga o enei kinase o nga mate e puta mai ana i nga mahi kino, penei i te mate pukupuku, mo te whakarite ranei i tetahi rongoa mo te rongoa i enei mate. Ko tona whakaahuatanga matū ko 1-oxa-6-aza-spiro- [2.5] octane-6-caboxylic waikawa tert-butyl, tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 6-aza -6-tert-butyloxycarbonyl-1-oxaspiro <2.5> octane, 1-oxa-6-aza-spiro [2,5] octane-6-carboxylic waikawa tert-butyl, 1-oxa-6-aza-spiro [2.5] octane-6-carboxylic acid ester, 1,1-dimethylthyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, 1,1-dimethylethyl 1-oxa-6-azaspiro [2.5] octane -6-carboxylate. Kei te whakamahia hei kaiwaenga rongoora. Ka whakamahia ano hoki hei kaiwawao i roto i nga waihanga o te wai. Kei te noho tenei hua (s) i runga i te kirimana APICMO. Mena kei te tiro koe i tenei whārangi hei kaiwhakamahi kore-rēhitatia, ko te utu (s) e whakaatuhia ana ko te Utu Rārangi. Hei tiro i to utu, takiuru ma te whakamahi i to tau nama, ka riro hei kaiwhakamahi rēhitatia mā te whakapā atu ki tetahi o o tatou ratonga Ratonga Kiritaki. Ki te whakatakoto i tetahi raupapa, whakapiri APICMO Ratonga Kiritaki . tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Specifications CAS 147804-30-6 CAS Min% 95.0 CAS Max% 98.0 Tau MDL MFCD07779385 Ki te KAUPAPA KI ULSBMKGFFFMGOI-UHFFFAOYSA-N Ingoa Toiina, Rauemi ranei tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Hauira Purapura Motuhēhē Pouaka Paenga Tae 97% Puka Puka Te Paara Mataara Packaging Pounamu tio Tātai rāpoi C11H19NO3 Taumaha Taumaha (g / mol) 213.277 Tuhinga o mua CC (C) (C) OC (= O) N1CCC2 (CC1) CO2 Tae White Ingoa Toiina, Rauemi ranei tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate Ko te Whakakuku 56 ° ki 58 ° C anga matou ≥96.0% tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Te Haumaru me te Whakaaetanga (147804-30-6) Te whakaahuatanga haumaru: Ko te mamae o te kiri. Ka nui te riri o te kanohi. Ka taea e te mamae o te rewharewha. Ahanoa i te pupuhi i te puehu / te paraoa / te hau / te kohu / te pupuhi / te pupuhi. tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate Kupu whakataki: Ahanoa i te pupuhi i te puehu / te paraoa / te hau / te kohu / te pupuhi / te pupuhi. Whakanohoia nga totikiri haumaru / kakahu tiaki / tiaki kanohi / kanohi. MĀ TE KAUPAPA: Whakakotahitia te wai ki te wai mo etahi meneti. Tangohia nga arotahi whakapiri, ki te mea kei te noho me te ngawari ki te mahi. Haere tonu ki te horoi. MĀ TE KAUPAPA: Tangohia ki te hau hou ka noho pai ki te hau. Kei te pupuri i te taonga. Tuhia nga ihirangi / putea kia rite ki nga tikanga o te rohe / rohe / motu / ao. WHAKATŪPATO: Ko nga korero i whakawhiwhia ki tenei pae tukutuku i whakawhanaketia i raro i nga ritenga o te ture a te Euroopu (EU) me te tika ki to maatau mohio, korero me te whakapono i te ra i tuhia ai. Ko nga korero i homai i hangaia hei awhina mo te whakahaere me te whakamahi haumaru. Kaore e whakaarohia he waahana, he kounga kounga. tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Articles Nafizal Hossain Nafizal Hossain, et al. Pūhui Spirocyclic, kaha CCR1 antagonists.Bioorg. Med. Chem. Tuhinga., 2013 Ratonga Hangarau: Kei to tatou kapa o nga kaitaiao nga wheako ki nga waahanga katoa o te rangahau, tae atu ki te Life Science, Te Hangarau Rauemi, te Hinengaro Hinairo, te Chromatography, te Tatauranga me etahi atu. tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Whakahua Puku & Tauira: Me nui ake nga waahanga mo to whakawhanaketanga, mahi mahi, rangahau ranei? ingoa hua ingoa * īmēra * waea Whakaahua * CAPTCHA * = karere tuku 2 arotake hoki Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) APICMO - 12 / 10 / 2018 He Kupu Whakataki-Korero ki te tert-butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate ( 147804-30-6 ) Kei te hanga me te whakahuihui i te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate i roto i te rahi me te rahi. I APICMO, ko o taatau hua e whai ana ki nga tikanga mana whakahaere o te cGMP. Mena ka hiahia koe ki te hoko i te nui o nga hua o tenei hua, na kei a koe i te waahi tika. Whakaritea tetahi tono ma te whakapiri atu ki to maatau kaiwhakahaere atawhai me nga kaiwhakahaere atawhai kiritaki. Mena ka hiahia koe ki te tiki atu i nga korero mo te hua, haere tonu ki te korero i runga. Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Whakaahuatanga Ko te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate ka taka ki te momo o nga pūhui spiro. Ko nga whakaaturanga e whakaatu ana ka taea e ia te whakakore i nga kinases, pēnei i te tyrosine. I muri mai, kua arahina ki te kitenga rongoā i runga i te maimoatanga me te whakahaere i nga matematetanga e pā ana ki te mate kinase, e whakaoho ana i te haere tonu o te mate pukupuku. Ahakoa ko te waitohu rongoa, ko te hua ano he takawaenga i roto i te whakawhitinga o te wai. Ko te tauira hanganga o te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6): Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Whakaritea Kore CAS. 147804-30-6 Ingoa matū 1-oxa-6-azaspiro [2.5] octane-6-carboxylic acid tert-butyl ester Te tihi (g / cm 3 ) 1.123 He tauira tahua C 11 H 19 NO 3 Ko te pupuhi (˚C) 297.62 Ko te tohu Flash (˚C) 133.8 Ingoa IUPAC Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Ko te ngao teitei (˚C) 55 - 59 Ko te taimaha o te koenga (g / mol) 213.277 Momoisotopic papatipu (g / mol) 213.136 Te āhua taiao mārō viivii 97% Te tahua hanganga Ngā Synonyms · 6- (tert-butoxycarbonyl) -1-oxa-6-azaspiro [2.5] octane · 6-boc-1-oxa-6-azaspiro [2.5] octane · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic waikawa waikawa tert-butyl · 1-oxa-6-azaspiro [2.5] octane-6-carboxylate · 1-oxa-6-azaspiro [2.5] octane-6-carboxylic waikawa waikawa tert-butyl · Tert-butyl-6-azaspiro [2.5] octane-1-oxa-6-carboxylate. Chemical & Āhuatanga Ā-Tinana o Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) ahua Ko te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate ko te paura whakamaara ma 147804-30-6 honohono Taea taapiri 2 Te waihanga wai Tau nama - 1 wae Whakaaetanga Whakaaetanga - 3 Koha 1 147804-30-6 Whakaritea Whakamahia Ingoa Tae Te uara rawa XLogP3-AA 1.1 Te pehanga tere (mmHg) 0.0 ± 6 Te Tae Tae Tae Taehia Kore 0 Te Tautuhi Tae Akerangi Atomorekore 0 Te horahanga polar mata 42.07 A ^ 2 Taurangi tohu 1.506 Atomope Atom Te tatau 0 Maatau Atom Count 15 Tae Whaimana 0 Makano (g / mol) 213.136 Tae Tae Tae Tautuhia 0 Tautuhia te Tohu Toro o Atom 0 He Canonicalized te tohu Ae Tuhinga 262 Rohe Rohe o Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate E iwa nga huarahi aratohu mo tenei hua. Kei raro nei etahi o nga tikanga kua whakaritea: Nga tono a 147804-30-6 Nga Mahi hei potae rongoa me te whakawhitinga whakawhitinga Ko te kaipupuri o etahi kinoa kinukore 147804-30-6 Hazard Description Maha atu ki te whakapataritari i nga kanohi, e arai ana ki te mate kino Ka meinga e ahau he mate kirika nui Ko te mumura o te pūnaha rewharewha Nga Mahi Haumaru I te Whakaaetanga ki te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) 1. Parenga Whaiaro Nga taputapu tiaki Me rite nga taputapu ki nga tohutohu a te kawanatanga, penei i nga ture a te Ropu Uropiha (EU) mo te iwi Pakeha, NIOSH ranei mo te United States. Me whakarite te tiaki i te tinana, te kanohi, te kanohi, te wahanga rewharewha, me te kiri. Whakamahia te momo N95 ranei momo P1 i runga i nga ture a rohe. Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Whakahaere Engineering Me whakarite kia nui rawa te hauora me te waatea o te waatea. 2. Nga Mahi Awhina Tuatahi Whakaaetanga kanohi Me horoi nga kanohi ki te wai rere makariri mo nga meneti 15 e whai mai nei. Haere ki te āwhina hauora mēnā kei te haere tonu te riri. Whakapā kiri Horoihia te wai me te hopi mo nga meneti 15. Ingoa Ko te awhina tuatahi e tika ana mo te mate o te mate. Murihia te mangai ki te inu me te inu i te iti atu i te hawhe rita o te wai ranei te waiu. A, no te kore e mohio te tangata, ka awhina wawe mai i te pokapū kawa, he toxicologist, he rata ranei. Inhalation Nekehia te patunga ki te ruma whakakii i te wa e noho pai ana. Te whakahaere i te manawa o te tangata kaore e mohio ana, ka hohoro te awhina a te taote. 3. Te whakahaere i te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate A, no te whakamahi, tirohia nga whakatupatotanga e whai ake nei: Ahanoa i te pupuhi i te pupuhi, te pungarehu, te rehu, te atu ranei o te waikura Whakauruhia nga taputapu tiaki whaiaro Whakamahia i roto i te taiwhanga mahi 4. Te nohoranga o te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) A, no te kore e whakamahi, Tiaki i roto i nga tikanga paerewa Tiakina te hua i raro i te hauota Paaturu i te oko rokiroki Me whakarite he waatea, he maroke, he makariri hoki te waahi rokiroki Kia mau ki te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate atu i nga kawakore kaha Katia te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate hei whakaiti i te uru 5. I muri Whakamahia I muri i te whakamahi i te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, Whakaorangia nga matū ka whakamahia me te pokekore ranei Horoi ringa Tangohia te hua kore i te taonga taketake taketake Mukua te mahinga mahi ma te horoi i nga waahanga 6. Mana Mana Whakanohoia nga hikohuinga e whaia ana e te tangata kia kaua e whakapiri ki nga paowa me te pupuhi o te mate, ka puta mai i te waahi. Whakanuihia te mura ki te mimiti wai, te paura makariri maroke, te waipiro waipiro, te haukini ranei. Ka whakawhirinaki nga kaitohu whakakore i runga i te kaha o te ahi me te kaihoko. 7. Nga Tae Whakamatau Mutu Kei roto tetahi taapiri, he waahi ranei. Whakawetohia te pupuhi ka whakamahi ranei i te pungarehu o te mimiti kia rite ki te onepu hei whakaeke i te matū. Makahia i roto i te kohao kati me te tuku kia rite ki nga tikanga whakahaere a te rohe. Whakaritea te pae mahi me te whakahurihuri. 8. Te mahinga me te whakahou o te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate He pai te hua i raro i nga tikanga whakahaere mana. 9. 147804-30-6 Rangahau Toi Whakamahia te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate hei otaota motuhake me te whakakore i te reira me te awhina o te kamupene riihi raihana raihana. 10. Mōhiohio Shipping Ko te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) he mea korerearea mo te hau, te whenua, te kaipuke kaipuke ranei. Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) Whakaara Ture Ko te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate (147804-30-6) kahore he whakatoranga motuhake, he haumaru ranei ki te taiao, te hauora tangata, te taiao ranei. he mea kaha tonu, he koiora ranei. Mo tenei take, kaore he mea kino, he kino ranei. Ko nga korero kei konei e rite ana ki nga whakaritenga o te ao. Taipitopito Hangarau Kei a tatou kairangahau te matauranga matatau i roto i nga mahi matatini me te ora, te matatini rangahau, te chromatography, te ariu matū, me te rangahau rangahau. Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate Te Puku Whakarite me te Poto He pai ki te rangahau, te whakawhanaketanga, me te whakawhitinga o nga matū? Whakaritehia nga rahi nui o te Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate mai ia tatou ka whiwhi i te whakahuatanga. Whakapā mai ki a matou kia waiho he raupapa. Bibliography National Center For Information Biotechnology, US. National Library of Medicine, Pubchem, Tert-butyl 1-oxa-6-azaspiro [2.5] octane-6-carboxylate, Mahinga 1-10. Nafizal Hossaina Svetl Ivano Jonas Bergarea Tomas Eriksson, Nga puhui Spirocyclic, te kaha o te CCR1, te Bioorganic & Medicinal Chemistry Rauemi Volume 23, Putanga 6, 15 Maehe 2013, Whārangi 1883-1886. Ko Nasrallah Gwendal Grelier Maria Ivana Lapuh Fernando J. Duran Benjamin Darses Philippe Dauban, Dirundi (II) -I whakamatauhia te Alkora Epoxidation me te Iodine (III) Kaiwaenga, page 12-14. Whakatauria 5 i roto i o 5 Apicmo - 05 / 17 / 2019 Ko te Tert-Butyl 1-Oxa-6-azaspiro [2.5] octane-6-carboxylate me te ratonga kua riro i ahau, he wheako pai Tāpiri i te arotake Whakakore whakautu Ka kore e whakaputaina tō wāhitau īmēra. tō whakatauranga Auau ... tino Pai Toharite E kore e kino Tino rawakore tō arotake * ingoa * īmēra * e pā ana Products 2,8-Diazaspiro[4.5]decan-3-one (561314-57-6) na APICMO Pānuitia atu 2-(tert-Butoxycarbonyl)-2,7-diazaspiro[3.5]nonane hydrochloride (929302-18-1) na APICMO Pānuitia atu 2-Oxa-6-azaspiro[3.4]octane (1408075-00-2) na APICMO Pānuitia atu Rapu hoki: Rapu Ngā Kāwai Hua Pūhui Spiro Azetidines Heterocycles Nga potae Nga pounamu Qungazolines Nga pungarehu Ngā pūhui chiral Ētahi atu pūhui Orthe Tūtohu hua Tuhinga Kāwai Tuhinga Kāwai Tīpako Kāwai Ko te tuhinga CMO (2) Ko te matauranga hauora (7) Nga Releata Hou 2019 CNS Treatment Drug Monosialotetrahexosylganglioside Sodium (GM1) Pig Brain (37758-47-7) 06 / 05 / 2019 Ko nga mea katoa e hiahia ana koe ki te mohio ki nga Pyridines 08 / 30 / 2018 Ko te nuinga o nga Taonga Hiko o te Ao 08 / 28 / 2018 Ko nga mea katoa e hiahia ana koe ki te mohio ki nga waehui spiro 08 / 28 / 2018 2-Chloro-5-methylpyrimidine: CAS (Ratonga Tapeke Tika) Waitohu 22536-61-4 08 / 18 / 2018 APICMO - Pakihi, APICMO & Pharmaceutical te hoko NOW Ko APICMO he kamupene rongoa kei te whanake i nga kaiwawao matua o nga raau hou. Kei te arotahi ki te whakarato i te raupapa katoa o nga ratonga whakahiato me te whakarite mo nga rangahau raau taero me nga pokapü whanaketanga me nga kamupene rongoa. Products Ētahi atu pūhui Nga pounamu Heterocycles Qungazolines Nga potae Ngā pūhui chiral Azetidines Nga pungarehu Pūhui Spiro to tatou Ratonga Ko te whakawhitinga ahurea me te kirimana R & D Pauna iti me te raupapa whakahau Poraka whare mo te kitenga raau taero Tukatuka R & D me te whanaketanga huarahi hou Whakapā mai Te hanga D, te papa 2, Nama 128, Road Xiangyin, Takiwa o Yangpu, 200433, Shanghai, Haina + 86 (1812) 4514004 [Tiakina email] © Copyright 2019 APICMO. 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